Search results for "haemoglobin foetal"

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Foetal erythrocytes exhibit an increased ability to scavenge for nitric oxide

1998

The presence of adult human whole blood inhibited in vitro relaxations of rat aortic rings by the nitric oxide (NO) donor S-nitroso-N-acetyl-DL-penicillamine (SNAP). Incubation with foetal blood containing the same concentration of haemoglobin produced a shift to the right of the relaxation curve. SNAP-induced vasorelaxations were more inhibited by dialysed solutions of haemoglobin than by the presence of erythrocytes in the organ bath, but there were no differences between the effect of adult or foetal haemoglobins. The presence of plasma from adult or foetal blood did not modify the effects of SNAP. Relaxations induced by endogenous, endothelium-derived, NO were more inhibited by foetal t…

Adultmedicine.medical_specialtyErythrocyteshaemoglobin foetalVasodilationIn Vitro TechniquesNitric OxideNitric oxidechemistry.chemical_compoundnewbornInternal medicinemedicineAnimalsHumansnitric oxide (NO)Aortavascular responseWhole bloodPharmacologyDose-Response Relationship DrugPenicillamineSnapAnatomyFetal BloodRatsRed blood cellEndocrinologymedicine.anatomical_structurechemistryVasoconstrictionCirculatory systemembryonic structuresHemoglobinerythrocyteBlood vessel

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